Products for Research Use Only

LXE408

CAT: 0013-GTR19170642-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170642-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LXE408 fumarate is a kinetoplastid-selective, orally active proteasome inhibitor with potent activity against Leishmania donovani, demonstrating both in vitro proteasome inhibition and cellular efficacy with low blood-brain barrier penetration. It represents a promising research tool for investigating novel treatments for visceral leishmaniasis in experimental models.
Product Name Alternative
1799330-15-6, 1799330-15-6 Free base, LXE 408 Fumarate, LXE408 Fumarate, LXE-408 Fumarate, LXE408 fumarate (1799330-15-6 Free base), Proteasome
Field of Research
Protein Biochemistry
Purity
98.10% (May vary between batches)
Solubility
DMSO:5.6 mg/mL (10.01 mM)
Smiles
OC (=O) \C=C\C (O) =O.Cc1nc (C) c (o1) C (=O) Nc1ccc (F) c (c1) -c1nc2ncc (cn2n1) -c1ncccc1C
Molecular Formula
C27H22FN7O6
Molecular Weight
559.51
Storage Conditions
-20°C
Notes
For research use only.