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SMI-16a

CAT: 0013-GTR19170552-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170552-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SMI-16a is a potent and selective ATP-competitive inhibitor of Pim-1 and Pim-2 kinases, with IC50 values of 150 nM and 20 nM, respectively. It demonstrates high selectivity, showing minimal activity against 57 other kinases. This compound is a valuable chemical probe for investigating Pim kinase function in cancer research and cellular signaling studies both in vitro and in vivo.
CAS Number
587852-28-6
Product Name Alternative
Inhibit, Inhibitor, SMI16a, SMI-16a, SMI 16a, Pim2, PIM1/2 Kinase Inhibitor VI, Pim, Pim kinases, Pim1
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
97.06% (May vary between batches)
Solubility
DMSO:150 mg/mL (569.67 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.19 mM)
Smiles
CCCOc1ccc (\C=C2\SC (=O) NC2=O) cc1
Molecular Formula
C13H13NO3S
Molecular Weight
263.31
Storage Conditions
-20°C
Notes
For research use only.

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BA6396-50SMI-16a
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A17157-10SMI-16a 10mg
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