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Dyrk1A-IN-9

CAT: 0804-HY-162597Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162597Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dyrk1A-IN-9 (Compound L9) is a moderately active DYRK1A inhibitor (IC50: 1.67 μM) . L9 shows neuroprotective activity by regulating the expression of Aβ and phosphorylation of Tau protein. Dyrk1A-IN-9 can be used for research of Alzheimer's disease[1].
UNSPSC
12352005
Target
DYRK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dyrk1a-in-9.html
Smiles
NC1=NN=NN1/N=C\C2=C(C3=CC=CC=C3)NN=C2
Molecular Formula
C11H10N8
Molecular Weight
254.25
References & Citations
[1]Si X, et al. Discovery of a novel DYRK1A inhibitor with neuroprotective activity by virtual screening and in vitro biological evaluation. Mol Divers. 2024 Jun 4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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