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PQM130

CAT: 0013-GTR19175923-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19175923-02Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PQM130 is a feruloyl-donepezil hybrid compound designed to counteract Aβ1-42 oligomer-induced neurotoxicity. It exhibits anti-inflammatory properties, making it a useful research tool for in vitro and in vivo studies investigating therapeutic strategies for Alzheimer's disease.
CAS Number
2089415-51-8
Product Name Alternative
PQM-130, PQM 130, PQM130, β Amyloid, βAmyloid, β-amyloid peptide, Inhibitor, inhibit, Abeta, Aβ1-42, b Amyloid, Amyloid-β, bAmyloid, BetaAmyloid, Beta Amyloid
Field of Research
Neuroscience
Purity
98.73% (May vary between batches)
Solubility
DMSO:5.5 mg/mL (14.42 mM)
Smiles
COc1cc (\C=C\C (=O) OCC2CCN (Cc3ccccc3) CC2) ccc1O
Molecular Formula
C23H27NO4
Molecular Weight
381.46
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(1-Benzylpiperidin-4-yl)methyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
CAS Number2089415-51-8
PubChem CID137643434
IUPAC Name(1-benzylpiperidin-4-yl)methyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
Molecular FormulaC23H27NO4
Molecular Weight381.5
XLogP4.1
Topological Polar Surface Area59
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Heavy Atom Count28
Formal Charge0
Complexity495
SMILES
COC1=C(C=CC(=C1)/C=C/C(=O)OCC2CCN(CC2)CC3=CC=CC=C3)O
InChI
InChI=1S/C23H27NO4/c1-27-22-15-18(7-9-21(22)25)8-10-23(26)28-17-20-11-13-24(14-12-20)16-19-5-3-2-4-6-19/h2-10,15,20,25H,11-14,16-17H2,1H3/b10-8+
InChIKey
QJDRBHVMOOPIGE-CSKARUKUSA-N
Chemical Structure
2D Structure
2D structure of (1-Benzylpiperidin-4-yl)methyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
CAS: 2089415-51-8
CID: 137643434
Formula: C23H27NO4
MW: 381.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight381.5
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Exact Mass381.19400834
Monoisotopic Mass381.19400834
Topological Polar Surface Area59 Ų
Heavy Atom Count28
Formal Charge0
Complexity495
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA8431-100PQM130
A18835-100PQM130 100mg
A18835-50PQM130 50mg
A18835-10PQM130 10mg
A18835-200PQM130 200mg
A18835-25PQM130 25mg
A18835-5PQM130 5mg
A18835-10mM-DPQM130 10mM * 1mL in DMSO

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