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Mizagliflozin

CAT: 0013-GTR19174578-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174578-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mizagliflozin is a potent and selective SGLT1 inhibitor (Ki=27 nM for human SGLT1) with 303-fold selectivity over SGLT2. This orally active anti-diabetic agent is used in research to study postprandial glucose control and has demonstrated potential for alleviating chronic constipation in preclinical models.
CAS Number
666843-10-3
Product Name Alternative
Gastrointestinal, Inhibitor, hSGLT1, hSGLT2, GSK 1614235, GSK1614235, GSK-1614235, GSK-1614235 free base, inhibit, KGA 3235, KGA3235, KGA-3235, KGA-3235 free base, Mizagliflozin, constipation, disorder, DSP3235, DSP-3235, DSP-3235 free base, DSP 3235, Chronic, antidiabetic, Sodium-dependent glucose cotransporters, SGLT, selective
Field of Research
Pharmacology & Drug Discovery
Purity
98.32% (May vary between batches)
Solubility
Methanol:250 mg/mL (442.74 mM) ; DMSO:100 mg/mL (177.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.08 mM)
Smiles
CC (C) c1[nH]nc (O[C@@H]2O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]2O) c1Cc1ccc (OCCCNCC (C) (C) C (N) =O) cc1C
Molecular Formula
C28H44N4O8
Molecular Weight
564.67
Storage Conditions
-20°C
Notes
For research use only.

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