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MA220607

CAT: 0804-HY-149734-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-149734-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MA220607 is an antibacterial agent with low hemolytic toxicity and a dual-target mechanism of action (MOA) . MA220607 promotes FtsZ protein polymerization, also increases the permeability of bacterial membranes and inhibits biofilm formation. The resistance rate of MA220607 is low, and the MICs against Gram-positive bacteria and Gram-negative bacteria are Table 0.062-2 μg/mL and 0.5-4 μg/mL, respectively) [1].
CAS Number
2922826-56-8
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ma220607.html
Purity
97.11
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
C[N+]1=CC(C2=CC=CC=C2)=C(/C=C/C3=CC=C(C(C)(C)C)C=C3)C=C1C4=CC=C(C(C)(C)C)C=C4.[I-]
Molecular Formula
C34H38IN
Molecular Weight
587.58
References & Citations
[1]Ma Y et al. New broad-spectrum and potent antibacterial agents with dual-targeting mechanism: Promoting FtsZ polymerization and disrupting bacterial membranes. Eur J Med Chem. 2023 Nov 7;263:115930.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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