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JW74

CAT: 0013-GTR19174393-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174393-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JW74 is a potent small molecule inhibitor of canonical Wnt signaling, exhibiting an IC50 of 420 nM against LiCl-induced pathway activation. This tool compound is valuable for in vitro and in vivo research investigating Wnt/β-catenin signaling in development, oncology, and stem cell biology.
CAS Number
863405-60-1
Product Name Alternative
Wnt, Wnt/b-catenin, Wnt/β-catenin, Wnt/betacatenin, βcatenin, JW 74, JW74, JW-74, inhibit, Inhibitor, bcatenin, beta-catenin, betacatenin
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
95.00% (May vary between batches)
Solubility
DMSO:45 mg/mL (98.57 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.38 mM)
Smiles
COc1ccc (cc1) -n1c (SCc2nc (no2) -c2ccc (C) cc2) nnc1-c1ccncc1
Molecular Formula
C24H20N6O2S
Molecular Weight
456.52
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
E1731-25mgJW74
A16219-100JW74 100mg
A16219-50JW74 50mg
A16219-10JW74 10mg
A16219-25JW74 25mg
A16219-5JW74 5mg
A16219-200JW74 200mg
A16219-10mM-DJW74 10mM * 1mL in DMSO

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