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CP-673451

CAT: 0013-GTR19171751-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171751-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CP-673451 is a potent and selective PDGFRα/β inhibitor (IC50: 10/1 nM) with demonstrated antiangiogenic and antitumor activity in research models. It exhibits over 450-fold selectivity against related kinases. This compound is utilized in vitro and in vivo to study PDGF signaling in cancer, fibrosis, and cardiovascular disease research.
CAS Number
343787-29-1
Product Name Alternative
CP673451, CP-673451, CP 673451, cKit, c-Kit, inhibit, Inhibitor, Platelet-derived growth factor receptor, PDGFR, PDGFRβ, PDGFRα, VEGFR1, VEGFR2
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.62% (May vary between batches)
Solubility
Ethanol:41.8 mg/mL (100.12 mM) ; DMSO:20.83 mg/mL (49.89 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.79 mM)
Smiles
COCCOc1ccc2n (cnc2c1) -c1ccc2cccc (N3CCC (N) CC3) c2n1
Molecular Formula
C24H27N5O2
Molecular Weight
417.5
Storage Conditions
-20°C
Notes
For research use only.

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B1337-1CP-673451
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A11350-5CP-673451 5mg

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