SIRT7 inhibitor 97491

CAT: 0013-GTR19170640-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19170640-01Size:1 mg

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Description

The small molecule inhibitor 97491 selectively targets SIRT7 (IC50 = 325 nM), functioning as a specific HDAC inhibitor. It induces apoptosis via caspase activation and is a valuable research tool for studying SIRT7's role in cancer biology and cellular processes in vitro.

CAS Number

1807758-81-1

Product Name Alternative

Deacetylase, Inhibitor, p53 K373/382, inhibit, Apoptosis, Sirtuin, SIRT7, SIRT7 inhibitor 97491, SIRT-7 inhibitor 97491, tumor

Field of Research

Cell Biology, Epigenetics & Chromatin, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology

Purity

99.75% (May vary between batches)

Solubility

DMSO:250 mg/mL (874.95 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (17.5 mM)

Smiles

Nc1cccc (Nc2ncc (o2) -c2ccc (Cl) cc2) c1

Molecular Formula

C15H12ClN3O

Molecular Weight

285.73

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

SIRT7 inhibitor 97491

CAS Number	1807758-81-1
PubChem CID	146018038
IUPAC Name	3-N-[5-(4-chlorophenyl)-1,3-oxazol-2-yl]benzene-1,3-diamine
Molecular Formula	C15H12ClN3O
Molecular Weight	285.73
XLogP	3.8
Topological Polar Surface Area	64.1
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	20
Formal Charge	0
Complexity	309

SMILES

C1=CC(=CC(=C1)NC2=NC=C(O2)C3=CC=C(C=C3)Cl)N

InChI

InChI=1S/C15H12ClN3O/c16-11-6-4-10(5-7-11)14-9-18-15(20-14)19-13-3-1-2-12(17)8-13/h1-9H,17H2,(H,18,19)

InChIKey

RMRVZWMKRCLSFX-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1807758-81-1

CID: 146018038

Formula: C15H12ClN3O

MW: 285.73

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	285.73
XLogP3	3.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	285.0668897
Monoisotopic Mass	285.0668897
Topological Polar Surface Area	64.1 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	309
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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