Products for Research Use Only

Trimethoprim

CAT: 0013-GTR19177269Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177269Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Trimethoprim (NSC-106568) is a small molecule antibacterial agent that primarily functions as a dihydrofolate reductase (DHFR) inhibitor. It is widely used in research to study antibiotic mechanisms and bacterial resistance, both in vitro and in animal infection models. Additionally, it exhibits inhibitory activity against cytochrome P450 2C8 and organic cation transporter 2.
CAS Number
738-70-5
Product Name Alternative
Aggregation, Antimicrobial, Antifolate, Antibiotic, Bacterial, BW 56-72, dihydrofolate, DHFR, DNA Synthesis, DNASynthesis, NIH 204, NIH204, NIH-204, NSC106568, NSC-106568, metabolism, Inhibitor, NSC 106568, inhibit, Influenza Virus, Hsps, folate, protein, RNASynthesis, RNA Synthesis, reductase, Shigellosis, Pneumocystis pneumonia, Thymidylate synthase, urinary tract infections, Trimethoprim, tetrahydrofolate
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.80% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.78 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:122 mg/mL (420.23 mM)
Smiles
COC1=CC (CC2=CN=C (N) N=C2N) =CC (OC) =C1OC
Molecular Formula
C14H18N4O3
Molecular Weight
290.32
Storage Conditions
-20°C
Notes
For research use only.

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