Mitemcinal

• Description :

  Mitemcinal (GM 611) is an oral motilin receptor agonist. Studies in rabbits and dogs have shown that it can promote defecation without causing severe diarrhea, increase stool weight without increasing water content in the rabbit constipation model, and reduce the time to first defecation in dogs. Mitemcinal may be a constipation suppressant due to its early onset and short duration of action[1].

• Product Name Alternative :

  GM 611

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/mitemcinal.html

• Smiles :

  C[C@]1(O2)[C@]([C@H]([C@]([C@H](C(O[C@H](CC)[C@](OC)(C)C([C@@H](C)C2=C(C)C1)=O)=O)C)([H])O[C@@]3([H])C[C@](C)([C@@H](O)[C@H](C)O3)OC)C)([H])O[C@@]4([H])[C@@H]([C@H](C[C@@H](C)O4)N(C)C(C)C)O

• Molecular Formula :

  C40H69NO12

• Molecular Weight :

  755.98

• References & Citations :

  [1]Mitsu Onoma, et al. Mitemcinal (GM-611), an orally active motilin receptor agonist, improves delayed gastric emptying in a canine model of diabetic gastroparesis. Clin Exp Pharmacol Physiol. 2008 Jul;35 (7) :788-96.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [154738-42-8]