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SR1078

CAT: 0013-GTR19170513-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170513-01Size:10 mg
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Description
SR1078 is a synthetic small molecule agonist that selectively activates the nuclear receptors RORα and RORγ. It is a valuable research tool for studying Th17 cell differentiation, cytokine production, and the role of these receptors in autoimmune and inflammatory diseases, as demonstrated in both cellular and animal models.
CAS Number
1246525-60-9
Product Name Alternative
SR 1078, SR1078, SR-1078, ROR, RORα, RORγ, RAR-related orphan receptor, Inhibitor, inhibit
Field of Research
Cell Biology, Immunology & Inflammation
Purity
>98%
Bioactivity
ROR agonist
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
OC (c1ccc (NC (=O) c2ccc (cc2) C (F) (F) F) cc1) (C (F) (F) F) C (F) (F) F
Molecular Formula
C17H10F9NO2
Molecular Weight
431.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[4- (1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl) phenyl]-4- (trifluoromethyl) benzamide

Chemical Information

N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)-4-(trifluoromethyl)benzamide
CAS Number1246525-60-9
PubChem CID17980288
IUPAC NameN-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-4-(trifluoromethyl)benzamide
Molecular FormulaC17H10F9NO2
Molecular Weight431.25
XLogP4.8
Topological Polar Surface Area49.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count11
Rotatable Bond Count3
Heavy Atom Count29
Formal Charge0
Complexity555
SMILES
C1=CC(=CC=C1C(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O)C(F)(F)F
InChI
InChI=1S/C17H10F9NO2/c18-15(19,20)11-3-1-9(2-4-11)13(28)27-12-7-5-10(6-8-12)14(29,16(21,22)23)17(24,25)26/h1-8,29H,(H,27,28)
InChIKey
DUXWIYXHHGNUJU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)-4-(trifluoromethyl)benzamide
CAS: 1246525-60-9
CID: 17980288
Formula: C17H10F9NO2
MW: 431.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight431.25
XLogP34.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count11
Rotatable Bond Count3
Exact Mass431.05678202
Monoisotopic Mass431.05678202
Topological Polar Surface Area49.3 Ų
Heavy Atom Count29
Formal Charge0
Complexity555
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
S5775-5mgSR1078
A15245-50SR1078 50mg
A15245-1SR1078 1mg
A15245-10SR1078 10mg
A15245-2SR1078 2mg
A15245-100SR1078 100mg
A15245-25SR1078 25mg
A15245-5SR1078 5mg
TBI4066-50MGSR1078, ROR agonist
A15245-10mM-DSR1078 10mM * 1mL in DMSO

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