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BGG463

CAT: 0013-GTR19170491-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170491-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BGG463 (K 0859) is a potent inhibitor of c-ABL-T334I, BCR-ABL, and the resistant BCR-ABL-T315I variant with respective IC50 values of 0.25, 0.09, and 0.590 μM. This compound is a valuable research tool for studying kinase signaling and resistance mechanisms in both cellular and biochemical assays relevant to oncology research.
CAS Number
890129-26-7
Product Name Alternative
K0859, K-0859, K03859, K-03859, K 0859, K 03859, inhibit, Inhibitor, Abl (T315I), Abl, BcrAbl, BGG 463, BGG463, BGG-463, c-Abl, Cyclin dependent kinase, CDK
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
95.05% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.91 mM) ; DMSO:125 mg/mL (216.05 mM)
Smiles
CN1CCN (Cc2ccc (NC (=O) c3cccc4cc (Oc5cc (NC (C) =O) ncn5) ccc34) cc2C (F) (F) F) CC1
Molecular Formula
C30H29F3N6O3
Molecular Weight
578.58
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

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GW1189-5mgBGG463
A20420-100BGG463 100mg
A20420-1BGG463 1mg
A20420-25BGG463 25mg
A20420-10BGG463 10mg
A20420-2BGG463 2mg
A20420-50BGG463 50mg
A20420-5BGG463 5mg
A20420-10mM-DBGG463 10mM * 1mL in DMSO

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