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M2I-1

CAT: 0013-GTR19170469-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170469-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M2I-1 is a first-in-class small molecule inhibitor that selectively disrupts the Mad2-Cdc20 protein-protein interaction, a key event in the spindle assembly checkpoint (SAC) . By interfering with Mad2's conformational dynamics, it serves as a valuable chemical probe for studying SAC function and aneuploidy in both cellular and biochemical assays.
CAS Number
312271-03-7
Product Name Alternative
Cdc20, inhibit, Mad2, M2I 1, M2I1, M-2I-1, M2I-1, Inhibitor, interaction, PPI, protein-protein
Field of Research
Cell Biology
Purity
97.61% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.94 mM) ; DMSO:45 mg/mL (111.25 mM)
Smiles
CC (C) CN (CC (C) C) c1ccc (C=C2C (=O) NC (=S) NC2=O) cc1[N+] ([O-]) =O
Molecular Formula
C19H24N4O4S
Molecular Weight
404.48
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
T4647-01M2I-1
A12247-25M2I-1 25mg
A12247-50M2I-1 50mg
A12247-10M2I-1 10mg
A12247-5M2I-1 5mg
A12247-2M2I-1 2mg
HY-100341RM2I-1 (Standard)
A12247-100M2I-1 100mg
A12247-10mM-DM2I-1 10mM * 1mL in DMSO
sc-59609MRP2 (M2I-4)

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