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SB297006

CAT: 0013-GTR19170448-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19170448-02Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB297006 is a potent and selective CCR3 antagonist (IC50 = 39 nM) that inhibits chemokine-induced calcium flux in vitro. It has demonstrated efficacy in vivo by reducing antigen-driven pulmonary recruitment of Th2 cells and eosinophils in mouse models, supporting its use in research on allergic inflammation and asthma.
CAS Number
58816-69-6
Product Name Alternative
SB 297006, SB297006, SB-297006, inhibit, Inhibitor, CC chemokine receptor, CCR3, CCR
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.59% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.68 mM) ; H2O:< 0.1 mg/mL (insoluble) ; DMSO:150 mg/mL (438.15 mM)
Smiles
CCOC (=O) [C@H] (Cc1ccc (cc1) [N+] ([O-]) =O) NC (=O) c1ccccc1
Molecular Formula
C18H18N2O5
Molecular Weight
342.35
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Ethyl (2S)-2-benzamido-3-(4-nitrophenyl)propanoate
CAS Number58816-69-6
PubChem CID9840971
IUPAC Nameethyl (2S)-2-benzamido-3-(4-nitrophenyl)propanoate
Molecular FormulaC18H18N2O5
Molecular Weight342.3
XLogP3.3
Topological Polar Surface Area101
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Heavy Atom Count25
Formal Charge0
Complexity463
SMILES
CCOC(=O)[C@H](CC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)C2=CC=CC=C2
InChI
InChI=1S/C18H18N2O5/c1-2-25-18(22)16(19-17(21)14-6-4-3-5-7-14)12-13-8-10-15(11-9-13)20(23)24/h3-11,16H,2,12H2,1H3,(H,19,21)/t16-/m0/s1
InChIKey
BEZXGSZPWXRHIN-INIZCTEOSA-N
Chemical Structure
2D Structure
2D structure of Ethyl (2S)-2-benzamido-3-(4-nitrophenyl)propanoate
CAS: 58816-69-6
CID: 9840971
Formula: C18H18N2O5
MW: 342.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight342.3
XLogP33.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Exact Mass342.12157168
Monoisotopic Mass342.12157168
Topological Polar Surface Area101 Ų
Heavy Atom Count25
Formal Charge0
Complexity463
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-103361-01SB297006
A19274-2SB297006 2mg
A19274-5SB297006 5mg
A19274-100SB297006 100mg
A19274-50SB297006 50mg
A19274-25SB297006 25mg
A19274-10SB297006 10mg
A19274-10mM-DSB297006 10mM * 1mL in DMSO

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