Products for Research Use Only

T863

CAT: 0013-GTR19170439-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170439-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
T-863 is a potent and selective oral DGAT1 inhibitor that binds the enzyme's acyl-CoA site to block cellular triacylglycerol synthesis. It has demonstrated efficacy in obese mouse models, reducing body weight, lowering hepatic and serum triglycerides, and improving insulin sensitivity, supporting its use in metabolic disease research.
CAS Number
701232-20-4
Product Name Alternative
Inhibit, Inhibitor, mono- acylglycerol acyltransferase, Diacylglycerol acyltransferase, DGAT3, DGAT-3, DGAT-1 inhibitor, DGAT1, DGAT 3, Diglyceride acyltransferase, acyl-CoA:cholesterol acyltransferase, Acyltransferase, T863, T-863, T 863
Field of Research
Metabolism Research
Purity
98.66% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (5.07 mM) ; DMSO:41.67 mg/mL (105.64 mM)
Smiles
CC1 (C) Oc2ncnc (N) c2N=C1c1ccc (cc1) [C@H]1CC[C@H] (CC (O) =O) CC1
Molecular Formula
C22H26N4O3
Molecular Weight
394.47
Storage Conditions
-20°C
Notes
For research use only.