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Simeprevir

CAT: 0013-GTR19170433-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170433-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Simeprevir (TMC435) is a small molecule NS3/4A protease inhibitor with potent anti-HCV activity, demonstrating an EC50 of 8 nM in replication assays. It has been widely used in both in vitro and in vivo research to study hepatitis C virus inhibition and combination antiviral therapies.
CAS Number
923604-59-5
Product Name Alternative
DNA/RNA Synthesis, Huh7-Luc, Hepatitis C virus, HCV NS3/4A protease, HCV, HCVProtease, HCV Protease, Inhibitor, immune responses, inhibit, Olysio, Virus replication, RNA-dependent RNA polymerase, Remdesivir, SARSCoV, SARS-CoV, SARS coronavirus, Simeprevir, TMC 435, TMC 435350, TMC-435350, TMC435, TMC435350, TMC-435, RdRp
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
99.45% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.33 mM) ; DMSO:55 mg/mL (73.34 mM)
Smiles
COc1ccc2c (O[C@@H]3C[C@@H]4[C@@H] (C3) C (=O) N (C) CCCC\C=C/[C@@H]3C[C@]3 (NC4=O) C (=O) NS (=O) (=O) C3CC3) cc (nc2c1C) -c1nc (cs1) C (C) C
Molecular Formula
C38H47N5O7S2
Molecular Weight
749.94
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
A3820-50Simeprevir

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