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Aftin-4

CAT: 0013-GTR19170282-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19170282-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aftin-4 is a γ-secretase activator that selectively increases Aβ1-42 production. This small molecule induces acute Alzheimer's disease-like pathology, including hippocampal learning deficits and mitochondrial alterations in rodent models, making it a valuable tool for in vivo and in vitro research on amyloid toxicity and AD mechanisms.
CAS Number
866893-90-5
Product Name Alternative
Abeta, Aftin 4, Aftin4, Aftin-4, b Amyloid, Amyloid-β, bAmyloid, BetaAmyloid, Beta Amyloid, Gammasecretase, Inhibitor, inhibit, γ secretase (Aβ42), β-amyloid peptide, βAmyloid, β Amyloid
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
98.51% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.43 mM) ; DMSO:55 mg/mL (149.26 mM)
Smiles
CC[C@H] (CO) Nc1nc (N (C) Cc2ccccc2) c2ncn (C (C) C) c2n1
Molecular Formula
C20H28N6O
Molecular Weight
368.48
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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BA8413-50Aftin-4
A17139-10Aftin-4 10mg
A17139-100Aftin-4 100mg
A17139-50Aftin-4 50mg
A17139-5Aftin-4 5mg
A17139-200Aftin-4 200mg
A17139-25Aftin-4 25mg
A17139-2Aftin-4 2mg
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