Products for Research Use Only
RegisterLogin

PZM21

CAT: 0013-GTR19170263-02Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19170263-02Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PZM21 is a potent and selective agonist of the μ-opioid receptor, exhibiting an EC50 of 1.8 nM. This research compound is utilized in vitro and in vivo to study analgesia, opioid signaling pathways, and the development of therapeutics with potentially reduced side effects.
CAS Number
1997387-43-5
Product Name Alternative
Inhibitor, inhibit, OpioidReceptor, Opioid Receptor, μ-opioid receptor, PZM 21, PZM21, PZM-21
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.59% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.53 mM) ; DMSO:27.5 mg/mL (76.07 mM)
Smiles
C[C@@H] (Cc1ccsc1) NC (=O) NC[C@H] (Cc1ccc (O) cc1) N (C) C
Molecular Formula
C19H27N3O2S
Molecular Weight
361.5
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-((2S)-2-(Dimethylamino)-3-(4-hydroxyphenyl)propyl)-N'-((1S)-1-methyl-2-(3-thienyl)ethyl)urea

PZM21 is a novel μ-opioid receptor (MOPr) ligand that has been reported to induce minimal arrestin recruitment and be devoid of the respiratory depressant effects characteristic of classical μ-opioid ligands such as morphine.

CAS Number1997387-43-5
PubChem CID121596705
IUPAC Name1-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-[(2S)-1-thiophen-3-ylpropan-2-yl]urea
Molecular FormulaC19H27N3O2S
Molecular Weight361.5
XLogP3.1
Topological Polar Surface Area92.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Heavy Atom Count25
Formal Charge0
Complexity400
SMILES
C[C@@H](CC1=CSC=C1)NC(=O)NC[C@H](CC2=CC=C(C=C2)O)N(C)C
InChI
InChI=1S/C19H27N3O2S/c1-14(10-16-8-9-25-13-16)21-19(24)20-12-17(22(2)3)11-15-4-6-18(23)7-5-15/h4-9,13-14,17,23H,10-12H2,1-3H3,(H2,20,21,24)/t14-,17-/m0/s1
InChIKey
MEDBIJOVZJEMBI-YOEHRIQHSA-N
Chemical Structure
2D Structure
2D structure of N-((2S)-2-(Dimethylamino)-3-(4-hydroxyphenyl)propyl)-N'-((1S)-1-methyl-2-(3-thienyl)ethyl)urea
CAS: 1997387-43-5
CID: 121596705
Formula: C19H27N3O2S
MW: 361.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight361.5
XLogP33.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Exact Mass361.18239829
Monoisotopic Mass361.18239829
Topological Polar Surface Area92.8 Ų
Heavy Atom Count25
Formal Charge0
Complexity400
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
526831PZM21
HY-101386RPZM21 (Standard)
A20586-25PZM21 25mg
A20586-2PZM21 2mg
A20586-100PZM21 100mg
A20586-50PZM21 50mg
A20586-5PZM21 5mg
A20586-1PZM21 1mg
A20586-10PZM21 10mg

Popular Products