Products for Research Use Only

GIBH-130

CAT: 0013-GTR19170209-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170209-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GIBH-130 is a potent small molecule inhibitor of neuroinflammation, demonstrating high efficacy in suppressing IL-1β release from activated microglia with an IC50 of 3.4 nM. Its application is valuable for studying neuroinflammatory pathways in both cellular and animal models of neurological disorders.
CAS Number
1252608-59-5
Product Name Alternative
Inhibitor, inhibit, IL-1β, ILReceptor, GIBH 130, GIBH130, GIBH-130, Interleukin Related, Interleukin, IL Receptor, TNF-α
Field of Research
Cell Biology, Immunology & Inflammation
Purity
99.52% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.55 mM) ; DMSO:27.5 mg/mL (76.3 mM)
Smiles
Cc1cc (nnc1C (=O) N1CCN (CC1) c1ncccn1) -c1ccccc1
Molecular Formula
C20H20N6O
Molecular Weight
360.41
Storage Conditions
-20°C
Notes
For research use only.