Products for Research Use Only

Cambinol

CAT: 0013-GTR19170039-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170039-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cambinol is a cell-permeable SIRT1 and SIRT2 inhibitor with substrate-competitive activity, also functioning as a brain-penetrant neutral sphingomyelinase (N-SMase) inhibitor. It induces apoptosis in BCL6-expressing lymphoma cells via p53 and BCL6 hyperacetylation and is used in oncology and neurology research, including in vivo studies on exosome biology and cancer models.
CAS Number
14513-15-6
Product Name Alternative
Cambinol, Apoptosis, NSC112546, NSC-112546, Inhibitor, inhibit, NSC 112546, SIRT2, SIRT1, SIRT1/2 Inhibitor IV, Sirtuin, Phospholipase
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology
Purity
98.02% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.55 mM) ; Ethanol:5 mg/mL (13.87 mM) ; DMSO:36 mg/mL (99.88 mM)
Smiles
Oc1ccc2ccccc2c1Cc1c ([nH]c (=S) [nH]c1=O) -c1ccccc1
Molecular Formula
C21H16N2O2S
Molecular Weight
360.43
Storage Conditions
-20°C
Notes
For research use only.