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Selamectin

CAT: 0013-GTR19169967-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169967-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Selamectin (UK-124114) is a macrocyclic lactone anthelmintic derived from ivermectin. It acts by potentiating glutamate- and GABA-gated chloride channels in parasitic nematodes, as demonstrated by its growth inhibitory effect at 0.1 μg/ml in Haemonchus contortus larval development assays. This compound is utilized in veterinary parasitology research and in vitro studies of anthelmintic mechanisms.
CAS Number
220119-17-5
Product Name Alternative
Parasite, inhibit, Multidrug resistance protein 1, MDR1, Inhibitor, ABCB1, Cl? Channels, CD243, Chloride channel, Chloride Channel, Chloridechannel, Cluster of differentiation 243, P-glycoprotein, Pgp, P-gp, P-gp (P-glycoprotein), Selamectin, UK-124114, UK124114, UK 124114
Field of Research
Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Purity
99.64% (May vary between batches)
Solubility
DMSO:90 mg/mL (116.89 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.29 mM)
Smiles
COC1CC (OC2C (C) \C=C\C=C3/COC4\C (=N\O) C (C) =CC (C (=O) OC5CC (C\C=C2/C) OC2 (CCC (C) C (O2) C2CCCCC2) C5) C34O) OC (C) C1O
Molecular Formula
C43H63NO11
Molecular Weight
769.96
Storage Conditions
-20°C
Notes
For research use only.

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