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CGP 57380

CAT: 0013-GTR19169927-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169927-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGP 57380 is a selective MNK1 inhibitor (IC50 = 2.2 μM) with minimal activity against related kinases like p38, JNK, ERK, PKC, and c-Src. It is a valuable research tool for studying MNK1's role in mRNA translation and oncogenesis in both cellular and animal models of cancer and inflammation.
CAS Number
522629-08-9
Product Name Alternative
Apoptosis, CGP 57380, CGP57380, CGP-57380, MAPK interacting kinase, MAP kinase interacting kinase, Inhibitor, Mitogen activated protein kinase interacting kinase, MNK, MNK1, MNK1 Inhibitor, MNK2, inhibit
Field of Research
Cell Biology, Signal Transduction
Purity
98.49% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.19 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:45 mg/mL (184.25 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Nc1ncnc2[nH]nc (Nc3ccc (F) cc3) c12
Molecular Formula
C11H9FN6
Molecular Weight
244.23
Storage Conditions
-20°C
Notes
For research use only.

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