Products for Research Use Only
RegisterLogin

CGS 21680 Hydrochloride

CAT: 0013-GTR19169926-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19169926-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CGS 21680 HCl is a potent and highly selective adenosine A2A receptor agonist (IC50=22 nM), exhibiting 140-fold selectivity for A2A over A1 receptors. It is widely used in vitro and in vivo to study adenosine signaling, neuroprotection, inflammation, and cardiovascular models.
CAS Number
124431-80-7
Product Name Alternative
Inhibitor, inhibit, CGS 21680, CGS 21680 HCl, CGS 21680 Hydrochloride, CGS21680, CGS-21680, CGS21680 Hydrochloride, CGS-21680 Hydrochloride, A2, Adenosine Receptor, AdenosineReceptor, P1 receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
96.74% (May vary between batches)
Solubility
DMSO:53.6 mg/mL (100 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.73 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cl.CCNC (=O) [C@H]1O[C@H] ([C@H] (O) [C@@H]1O) n1cnc2c (N) nc (NCCc3ccc (CCC (O) =O) cc3) nc12
Molecular Formula
C23H29N7O6·HCl
Molecular Weight
535.98
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

CGS 21680 Hydrochloride
CAS Number124431-80-7
PubChem CID10256643
IUPAC Name3-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid;hydrochloride
Molecular FormulaC23H30ClN7O6
Molecular Weight536.0
Topological Polar Surface Area198
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count11
Rotatable Bond Count10
Heavy Atom Count37
Formal Charge0
Complexity754
SMILES
CCNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=C(N=C32)NCCC4=CC=C(C=C4)CCC(=O)O)N)O)O.Cl
InChI
InChI=1S/C23H29N7O6.ClH/c1-2-25-21(35)18-16(33)17(34)22(36-18)30-11-27-15-19(24)28-23(29-20(15)30)26-10-9-13-5-3-12(4-6-13)7-8-14(31)32;/h3-6,11,16-18,22,33-34H,2,7-10H2,1H3,(H,25,35)(H,31,32)(H3,24,26,28,29);1H/t16-,17+,18-,22+;/m0./s1
InChIKey
QPHVMNOEKKJYJO-MJWSIIAUSA-N
Chemical Structure
2D Structure
2D structure of CGS 21680 Hydrochloride
CAS: 124431-80-7
CID: 10256643
Formula: C23H30ClN7O6
MW: 536.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight536.0
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count11
Rotatable Bond Count10
Exact Mass535.1946094
Monoisotopic Mass535.1946094
Topological Polar Surface Area198 Ų
Heavy Atom Count37
Formal Charge0
Complexity754
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19184342-01CGS 21680
GTR19231897-01CGS-21680
GTR19248610-01CGS 21680 sodium
GTR19154687-01CGS 21680 HCl Hydrate
GTR19273255-01CGS-17867A hydrochloride
GTR19258788-01CGS 24592
GTR19211354-01CGS 13928C
GTR19210102-01Cgs 26303
GTR19208410-01CGS 22745
GTR19199383-01CGS 35601

Alternative Products

CatalogName
HY-13201A-01CGS 21680 (Hydrochloride)
254951-01CGS 21680 hydrochloride
217151Adenosine A2A Receptor Agonist I, Hydrochloride (CGS 21680)
A3304-50CGS 21680
TCL-00273-01CGS 21680 sodium
MBS3841676-01CGS 21680 HCl
A11354-50CGS 21680 50mg

Popular Products