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EI1

CAT: 0013-GTR19169885-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169885-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EI1 is a potent and selective small molecule inhibitor of EZH2, demonstrating IC50 values of 15 nM against wild-type and 13 nM against the Y641F mutant. It is widely used in vitro and in vivo to study epigenetic mechanisms in oncology, particularly for cancers driven by EZH2 dysregulation such as lymphomas.
CAS Number
1418308-27-6
Product Name Alternative
Apoptosis, inhibit, KB 145943, KB145943, KB-145943, EI 1, EI1, EI-1, EZH2, Ezh2 inhibitor, Inhibitor, HistoneMethyltransferase, Histone Methyltransferase
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
99.93% (May vary between batches)
Solubility
H2O:Insoluble; DMSO:12.5 mg/mL (32.01 mM)
Smiles
CCC (CC) n1ccc2c (cc (cc12) C#N) C (=O) NCc1c (C) cc (C) [nH]c1=O
Molecular Formula
C23H26N4O2
Molecular Weight
390.48
Storage Conditions
-20°C
Notes
For research use only.

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