Products for Research Use Only
RegisterLogin

HO-3867

CAT: 0013-GTR19169833-06Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19169833-06Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HO-3867 is a curcumin analog that functions as a selective STAT3 inhibitor. It is utilized in cancer research to study STAT3-driven pathways, demonstrating activity in both in vitro cell-based assays and in vivo tumor models.
CAS Number
1172133-28-6
Product Name Alternative
Apoptosis, inhibit, Inhibitor, HO 3867, HO3867, HO-3867, STAT3, STAT
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
91.18% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:6 mg/mL (12.92 mM) ; DMSO:11 mg/mL (23.68 mM) ;10% DMSO+90% Corn Oil:1 mg/mL (2.15 mM)
Smiles
CC1 (C) C=C (CN2C\C (=C/c3ccc (F) cc3) C (=O) \C (C2) =C\c2ccc (F) cc2) C (C) (C) N1O
Molecular Formula
C28H30F2N2O2
Molecular Weight
464.55
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-1-[(1-hydroxy-2,2,5,5-tetramethylpyrrol-3-yl)methyl]piperidin-4-one
CAS Number1172133-28-6
PubChem CID46871899
IUPAC Name(3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-1-[(1-hydroxy-2,2,5,5-tetramethylpyrrol-3-yl)methyl]piperidin-4-one
Molecular FormulaC28H30F2N2O2
Molecular Weight464.5
XLogP4.1
Topological Polar Surface Area43.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count34
Formal Charge0
Complexity816
SMILES
CC1(N(C(C(=C1)CN2C/C(=C\C3=CC=C(C=C3)F)/C(=O)/C(=C/C4=CC=C(C=C4)F)/C2)(C)C)O)C
InChI
InChI=1S/C28H30F2N2O2/c1-27(2)15-23(28(3,4)32(27)34)18-31-16-21(13-19-5-9-24(29)10-6-19)26(33)22(17-31)14-20-7-11-25(30)12-8-20/h5-15,34H,16-18H2,1-4H3/b21-13+,22-14+
InChIKey
PWZQFTQMMAIRRM-JFMUQQRKSA-N
Chemical Structure
2D Structure
2D structure of (3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-1-[(1-hydroxy-2,2,5,5-tetramethylpyrrol-3-yl)methyl]piperidin-4-one
CAS: 1172133-28-6
CID: 46871899
Formula: C28H30F2N2O2
MW: 464.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight464.5
XLogP34.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass464.22753453
Monoisotopic Mass464.22753453
Topological Polar Surface Area43.8 Ų
Heavy Atom Count34
Formal Charge0
Complexity816
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR18009566HO Antibody
GTR19211091-01HO-3089
GTR18069205-01HO Polyclonal Antibody
GTR19216784-01HO-PEG13-OH
GTR19216783-01HO-PEG16-OH
GTR19215840-01HO-PEG11-OH
GTR19226504-01HO-PEG8-CH2CH2COOH
GTR19225979-01HO-PEG12-CH2COOH
GTR19225946-01HO-PEG24-CH2COOH
GTR19225924-01HO-PEG6-CH2COOH

Alternative Products

CatalogName
406527HO-3867
A14264-25HO-3867 25mg
A14264-50HO-3867 50mg
A14264-1HO-3867 1mg
A14264-100HO-3867 100mg
A14264-10HO-3867 10mg

Popular Products