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LDC000067

CAT: 0013-GTR19169807-07Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169807-07Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LDC000067 is a potent and selective CDK9 inhibitor with an IC50 of 44±10 nM. It is a valuable research tool for studying transcriptional regulation in oncology and virology, applicable in both in vitro biochemical assays and cellular mechanism-of-action studies.
CAS Number
1073485-20-7
Product Name Alternative
LDC 000067, LDC 067, LDC000067, LDC-000067, LDC067, LDC-067, Inhibitor, inhibit, Cyclin dependent kinase, CDK9, CDK6, CDK, CDK1, CDK2, CDK4, Apoptosis
Field of Research
Cell Biology
Purity
98.08% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:69 mg/mL (186.27 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.4 mM)
Smiles
COc1ccccc1-c1cc (Nc2cccc (CS (N) (=O) =O) c2) ncn1
Molecular Formula
C18H18N4O3S
Molecular Weight
370.43
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(3-{[6-(2-Methoxyphenyl)pyrimidin-4-yl]amino}phenyl)methanesulfonamide
CAS Number1073485-20-7
PubChem CID25104564
IUPAC Name[3-[[6-(2-methoxyphenyl)pyrimidin-4-yl]amino]phenyl]methanesulfonamide
Molecular FormulaC18H18N4O3S
Molecular Weight370.4
XLogP2.2
Topological Polar Surface Area116
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count26
Formal Charge0
Complexity539
SMILES
COC1=CC=CC=C1C2=CC(=NC=N2)NC3=CC=CC(=C3)CS(=O)(=O)N
InChI
InChI=1S/C18H18N4O3S/c1-25-17-8-3-2-7-15(17)16-10-18(21-12-20-16)22-14-6-4-5-13(9-14)11-26(19,23)24/h2-10,12H,11H2,1H3,(H2,19,23,24)(H,20,21,22)
InChIKey
GGQCIOOSELPMBB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (3-{[6-(2-Methoxyphenyl)pyrimidin-4-yl]amino}phenyl)methanesulfonamide
CAS: 1073485-20-7
CID: 25104564
Formula: C18H18N4O3S
MW: 370.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight370.4
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass370.10996162
Monoisotopic Mass370.10996162
Topological Polar Surface Area116 Ų
Heavy Atom Count26
Formal Charge0
Complexity539
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B4754-10LDC000067
A14273-25LDC000067 25mg
A14273-2LDC000067 2mg
A14273-10LDC000067 10mg
A14273-5LDC000067 5mg
A14273-100LDC000067 100mg
A14273-50LDC000067 50mg
MBS130601-01LDC000067(LDC-067)

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