Products for Research Use Only
RegisterLogin

Siremadlin

CAT: 0013-GTR19169632-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19169632-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Siremadlin (NVP-HDM201) is a potent, specific, and orally bioavailable small molecule inhibitor of the p53-MDM2 interaction. It is used in cancer research to reactivate p53 in vitro and has demonstrated antitumor efficacy in vivo in xenograft models of wild-type p53 tumors.
CAS Number
1448867-41-1
Product Name Alternative
E1Enzyme, E2 conjugating enzyme, E2 Enzyme, E1/E2/E3 Enzyme, E1 Enzyme, E1 activating enzyme, inhibit, p53-MDM2, NVP-HDM 201, NVP-HDM201, NVP-HDM-201, HDM201, HDM-201, HDM 201, Inhibitor, MDM-2/p53, E3 Enzyme, E2Enzyme, E3 ligating enzyme, E3Enzyme, Siremadlin, Ubiquitin ligase, Ubiquitin conjugating enzyme, Ubiquitin activating enzyme
Field of Research
Cell Biology, Protein Biochemistry
Purity
97.77% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.6 mM) ; DMSO:56.75 mg/mL (102.18 mM)
Smiles
COc1ncc (-c2nc3C (=O) N ([C@H] (c3n2C (C) C) c2ccc (Cl) cc2) c2cc (Cl) cn (C) c2=O) c (OC) n1
Molecular Formula
C26H24Cl2N6O4
Molecular Weight
555.41
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
206159Siremadlin
C13534-5mgSiremadlin (HDM201)
MBS5753607Siremadlin R Enantiomer
HY-18658A-01Siremadlin (R Enantiomer)

Popular Products