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CK-869

CAT: 0013-GTR19169449-06Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169449-06Size:100 mg
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Description
CK-869 is a cell-permeable small molecule inhibitor of the Arp2/3 complex with an IC50 of 7 μM. It serves as a valuable chemical probe for studying actin cytoskeleton dynamics in cellular migration, endocytosis, and pathogen invasion in both in vitro and in vivo research models.
CAS Number
388592-44-7
Product Name Alternative
CK 869, CK869, CK-869, Arp2/3 Complex, Actin-related protein 2/3 complex, MicrotubuleAssociated, Microtubule Associated, inhibit, Inhibitor
Field of Research
Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:75 mg/mL (190.22 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.07 mM)
Smiles
COc1ccc (N2C (SCC2=O) c2cccc (Br) c2) c (OC) c1
Molecular Formula
C17H16BrNO3S
Molecular Weight
394.28
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone
CAS Number388592-44-7
PubChem CID3574452
IUPAC Name2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one
Molecular FormulaC17H16BrNO3S
Molecular Weight394.3
XLogP4
Topological Polar Surface Area64.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count23
Formal Charge0
Complexity425
SMILES
COC1=CC(=C(C=C1)N2C(SCC2=O)C3=CC(=CC=C3)Br)OC
InChI
InChI=1S/C17H16BrNO3S/c1-21-13-6-7-14(15(9-13)22-2)19-16(20)10-23-17(19)11-4-3-5-12(18)8-11/h3-9,17H,10H2,1-2H3
InChIKey
MVWNPZYLNLATCH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone
CAS: 388592-44-7
CID: 3574452
Formula: C17H16BrNO3S
MW: 394.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight394.3
XLogP34
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass393.00343
Monoisotopic Mass393.00343
Topological Polar Surface Area64.1 Ų
Heavy Atom Count23
Formal Charge0
Complexity425
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
B5788-25CK 869
T5860-01CK-869
A20970-200CK-869 200mg
A20970-1CK-869 1mg
A20970-25CK-869 25mg
A20970-100CK-869 100mg
A20970-50CK-869 50mg
A20970-10CK-869 10mg
A20970-5CK-869 5mg

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