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Ginkgetin

CAT: 0013-GTR19169284-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19169284-02Size:5 mg
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Description
Ginkgetin is a bioactive biflavone with demonstrated antiviral, anti-inflammatory, and anticancer properties. It acts as a STAT3 inhibitor, induces apoptosis in prostate cancer cells in vitro, and shows neuroprotective effects in models of Parkinson's disease, supporting research in oncology, neurology, and immunology.
CAS Number
481-46-9
Product Name Alternative
Neuroprotective, inhibit, Inhibitor, leaves, Ginkgetin, Ginkgo, bcatenin, biloba, biflavone, Autophagy, anti-fungal, anti-inflammatory, anti-tumor, Apoptosis, beta-catenin, betacatenin, COX-2, signaling, Wnt/β-catenin, Wnt/betacatenin, Wnt/b-catenin, Wnt, STAT3, βcatenin
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.63% (May vary between batches)
Solubility
DMSO:55 mg/mL (97.09 mM)
Smiles
COc1cc (O) c2c (c1) oc (cc2=O) -c1ccc (OC) c (c1) -c1c (O) cc (O) c2c1oc (cc2=O) -c1ccc (O) cc1
Molecular Formula
C32H22O10
Molecular Weight
566.51
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Ginkgetin

Ginkgetin is a biflavonoid that is the 7,4'-dimethyl ether derivative of amentoflavone. Isolated from Ginkgo biloba and Dioon, it exhibits anti-HSV-1, antineoplastic and inhibitory activities towards arachidonate 5-lipoxygenase and cyclooxygenase 2. It has a role as a metabolite, an antineoplastic agent, a cyclooxygenase 2 inhibitor, an anti-HSV-1 agent and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is a hydroxyflavone, a methoxyflavone, a ring assembly and a biflavonoid. It is functionally related to an amentoflavone.

CAS Number481-46-9
PubChem CID5271805
IUPAC Name5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one
Molecular FormulaC32H22O10
Molecular Weight566.5
XLogP5.7
Topological Polar Surface Area152
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Heavy Atom Count42
Formal Charge0
Complexity1080
SMILES
COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OC)O)C4=C(C=C(C5=C4OC(=CC5=O)C6=CC=C(C=C6)O)O)O
InChI
InChI=1S/C32H22O10/c1-39-18-10-20(34)30-23(37)13-27(41-28(30)11-18)16-5-8-25(40-2)19(9-16)29-21(35)12-22(36)31-24(38)14-26(42-32(29)31)15-3-6-17(33)7-4-15/h3-14,33-36H,1-2H3
InChIKey
AIFCFBUSLAEIBR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Ginkgetin
CAS: 481-46-9
CID: 5271805
Formula: C32H22O10
MW: 566.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight566.5
XLogP35.7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count5
Exact Mass566.12129689
Monoisotopic Mass566.12129689
Topological Polar Surface Area152 Ų
Heavy Atom Count42
Formal Charge0
Complexity1080
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
300333Ginkgetin
HY-N0889R-01Ginkgetin (Standard)
A12061-20Ginkgetin 20mg
A12061-50Ginkgetin 50mg
A12061-25Ginkgetin 25mg
A12061-1Ginkgetin 1mg
A12061-200Ginkgetin 200mg
A12061-100Ginkgetin 100mg
A12061-10Ginkgetin 10mg

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