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Coptisine

CAT: 0013-GTR19168940-05Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168940-05Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Coptisine is a bioactive alkaloid with research applications in cardioprotection, oncology, and metabolic studies. It demonstrates anti-apoptotic and anti-inflammatory effects in myocardial ischemia-reperfusion models and exhibits anti-metastatic activity in breast cancer cell lines like MDA-MB-231 by modulating MMP-9 and TIMP-1.
CAS Number
3486-66-6
Product Name Alternative
Coptisin, Coptisine, Inhibitor, inhibit, Indoleamine 2,3-Dioxygenase (IDO), Indoleamine 2,3Dioxygenase (IDO), Indoleamine2,3Dioxygenase, Indoleamine2,3Dioxygenase (IDO), Indoleamine 2,3-Dioxygenase, IDO
Field of Research
Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
DMSO:3.91 mg/mL (12.21 mM)
Smiles
C1=2C=3C (=CC4=C (C3) OCO4) CC[N+]1=CC=5C (C2) =CC=C6C5OCO6
Molecular Formula
C19H14NO4
Molecular Weight
320.32
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Coptisine

Coptisine is a natural product found in Coptis japonica. It has a role as a metabolite.

CAS Number3486-66-6
PubChem CID72322
IUPAC Name5,7,17,19-tetraoxa-13-azoniahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-1(13),2,4(8),9,14,16(20),21,23-octaene
Molecular FormulaC19H14NO4+
Molecular Weight320.3
XLogP3.5
Topological Polar Surface Area40.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Heavy Atom Count24
Formal Charge1
Complexity502
SMILES
C1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6
InChI
InChI=1S/C19H14NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,5-8H,3-4,9-10H2/q+1
InChIKey
XYHOBCMEDLZUMP-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Coptisine
CAS: 3486-66-6
CID: 72322
Formula: C19H14NO4+
MW: 320.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight320.3
XLogP33.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass320.09228293
Monoisotopic Mass320.09228293
Topological Polar Surface Area40.8 Ų
Heavy Atom Count24
Formal Charge1
Complexity502
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
N1737-20Coptisine
M18873-01Coptisine chloride
N2494-20Coptisine Sulfate
A14548-50Coptisine 50mg
A14548-1Coptisine 1mg
HY-N0736-01Coptisine (chloride)
A14548-25Coptisine 25mg

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