Mouse anti Rb1 [1F8]: Horseradish peroxidase (HRP)

• Gene Name:

  [Rb1]

• Reactivity:

  Mouse, Human

• Specificity:

  This antibody recognises retinoblastoma-associated protein (RB), a 105kDa tumour suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma.

• Short Name:

  [Rb1]

• CAS Number:

  9007-83-4