Products for Research Use Only

N-Desmethylclozapine

CAT: 0013-GTR19168596-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168596-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Desmethylclozapine is a bioactive metabolite of clozapine, functioning as a potent 5-HT2C receptor antagonist (IC50: 7.1 nM), a dopamine D4 receptor antagonist, and a δ-opioid receptor agonist. It is a valuable research tool for investigating neuropsychiatric disorders and receptor pharmacology in both in vitro and in vivo experimental models.
CAS Number
6104-71-8
Product Name Alternative
5HTReceptor, 5-HT2C, 5HT Receptor, DrugMetabolite, Dopamine Receptor, Drug Metabolite, DopamineReceptor, Desmethylclozapine, D4, Inhibitor, Normethylclozapine, Norclozapine, Muscarinic acetylcholine receptor, N Desmethylclozapine, inhibit, NDesmethylclozapine, N-Desmethylclozapine, mAChR, Opioid Receptor, OpioidReceptor, δ-opioid receptor, Virus Protease, VirusProtease
Field of Research
Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
97.25% (May vary between batches)
Solubility
DMSO:125 mg/mL (399.62 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.39 mM) ; Ethanol:30 mg/mL (95.91 mM)
Smiles
Clc1ccc2N=c3ccccc3=C (Nc2c1) N1CCNCC1
Molecular Formula
C17H17ClN4
Molecular Weight
312.8
Storage Conditions
-20°C
Notes
For research use only.