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AMZ30

CAT: 0013-GTR19168572-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168572-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMZ30 is a potent and selective small molecule inhibitor of the methylesterase PME-1, exhibiting an IC50 of 600 nM. It effectively reduces levels of demethylated PP2A in cellular models, making it a valuable chemical probe for studying PP2A regulation in cancer and neurodegenerative disease research.
CAS Number
1313613-09-0
Product Name Alternative
PME-1, inhibit, Inhibitor, AMZ 30, AMZ30, AMZ-30
Field of Research
Metabolism Research, Signal Transduction
Purity
98.81% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (48.76 mM)
Smiles
[O-][N+] (=O) c1cccc (c1) S (=O) (=O) n1cccc1\C=C (/C#N) S (=O) (=O) c1ccc (F) cc1
Molecular Formula
C19H12FN3O6S2
Molecular Weight
461.44
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(E)-2-(4-fluorophenyl)sulfonyl-3-[1-(3-nitrophenyl)sulfonylpyrrol-2-yl]prop-2-enenitrile

2-(4-fluorophenyl)sulfonyl-3-[1-(3-nitrophenyl)sulfonyl-2-pyrrolyl]-2-propenenitrile is a sulfonamide.

CAS Number1313613-09-0
PubChem CID44607965
IUPAC Name(E)-2-(4-fluorophenyl)sulfonyl-3-[1-(3-nitrophenyl)sulfonylpyrrol-2-yl]prop-2-enenitrile
Molecular FormulaC19H12FN3O6S2
Molecular Weight461.4
XLogP3
Topological Polar Surface Area160
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Heavy Atom Count31
Formal Charge0
Complexity963
SMILES
C1=CC(=CC(=C1)S(=O)(=O)N2C=CC=C2/C=C(\C#N)/S(=O)(=O)C3=CC=C(C=C3)F)[N+](=O)[O-]
InChI
InChI=1S/C19H12FN3O6S2/c20-14-6-8-17(9-7-14)30(26,27)19(13-21)11-15-4-2-10-22(15)31(28,29)18-5-1-3-16(12-18)23(24)25/h1-12H/b19-11+
InChIKey
GUCUORSUHTZMBW-YBFXNURJSA-N
Chemical Structure
2D Structure
2D structure of (E)-2-(4-fluorophenyl)sulfonyl-3-[1-(3-nitrophenyl)sulfonylpyrrol-2-yl]prop-2-enenitrile
CAS: 1313613-09-0
CID: 44607965
Formula: C19H12FN3O6S2
MW: 461.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight461.4
XLogP33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass461.01515562
Monoisotopic Mass461.01515562
Topological Polar Surface Area160 Ų
Heavy Atom Count31
Formal Charge0
Complexity963
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
M19957-01AMZ30
A17131-1AMZ30 1mg
A17131-100AMZ30 100mg
A17131-10AMZ30 10mg
A17131-25AMZ30 25mg
A17131-50AMZ30 50mg
A17131-5AMZ30 5mg
A17131-10mM-DAMZ30 10mM * 1mL in DMSO

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