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PF-9366

CAT: 0013-GTR19168562-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168562-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-9366 is a potent and selective small molecule inhibitor of methionine adenosyltransferase 2A (MAT2A), exhibiting an IC50 of 420 nM and a Kd of 170 nM. It is a valuable chemical probe for researching methyl metabolism in cancers, with utility in both in vitro biochemical assays and in vivo xenograft studies.
CAS Number
72882-78-1
Product Name Alternative
MAT, Mat2A, Inhibitor, MethionineAdenosyltransferase, MethionineAdenosyltransferase (MAT), Methionine Adenosyltransferase, Methionine Adenosyltransferase (MAT), inhibit, PF 9366, PF9366, PF-9366
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
Methionine adenosyltransferase 2A inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
CN (C) CCc1nnc2cc (-c3ccccc3) c3cc (Cl) ccc3n12
Molecular Formula
C20H19ClN4
Molecular Weight
350.85
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2- (7-Chloro-5-phenyl) -[1,2,4]triazolo[4,3-a]quinoline-1-yl) -N, N, dimethylethanamine

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