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TP0463518

CAT: 0013-GTR19168477-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168477-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TP-0463518 is a potent small molecule inhibitor of HIF prolyl hydroxylase (PHD), demonstrating high activity with IC50 values of 13 nM for human PHD2 and 18 nM for rat PHD2. This compound is a valuable research tool for studying hypoxia signaling pathways and has been utilized in both cellular and animal models to investigate conditions like anemia and ischemia.
CAS Number
1558021-37-6
Product Name Alternative
TP-0463518, TP0463518, TP 0463518, PHD3, PHD1, PHD2, inhibit, Inhibitor, HIF/HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF, HIFs, HIFProlylHydroxylase, HIF-PH, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, Hypoxia-inducible factors
Field of Research
Epigenetics & Chromatin, Metabolism Research
Purity
99.43% (May vary between batches)
Solubility
DMSO:110 mg/mL (254.73 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.26 mM)
Smiles
OC (=O) CNC (=O) C1=C (O) CCN (Cc2ccc (Oc3ccc (Cl) cc3) nc2) C1=O
Molecular Formula
C20H18ClN3O6
Molecular Weight
431.83
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

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BA7806-10TP0463518
A20183-100TP0463518 100mg
A20183-10TP0463518 10mg
A20183-50TP0463518 50mg
A20183-25TP0463518 25mg
A20183-5TP0463518 5mg
A20183-10mM-DTP0463518 10mM * 1mL in DMSO

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