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BMS 599626 2HCl

CAT: 0013-GTR19168471-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168471-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS 599626 dihydrochloride (CAS 873837-23-1 (HCl) ), also known as AC480 dihydrochloride, is a potent and selective ATP-competitive inhibitor of HER1/EGFR and HER2 tyrosine kinases, with IC50 values of 20 nM and 30 nM, respectively. It demonstrates significantly weaker activity against HER4 and many other kinases. This compound has been utilized in preclinical research to investigate HER-driven tumorigenesis in both cellular and animal models.
CAS Number
1781932-33-9
Product Name Alternative
BMS 599626 2HCl (873837 23 1 (HCl) ), BMS 599626 2HCl (873837231 (HCl) ), BMS 599626 2HCl (873837-23-1 (HCl) ), AC 480, AC 480 Dihydrochloride, AC480, AC-480, AC480 Dihydrochloride, AC480 dihydrochloride, AC-480 Dihydrochloride, HER4, HER2, HER1
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.94% (May vary between batches)
Solubility
H2O:3 mg/mL (4.97 mM) ; DMSO:95 mg/mL (157.42 mM)
Smiles
O=C (OC[C@@H]1COCCN1) NC2=CN3C (C (NC4=CC=C (N (N=C5) CC6=CC (F) =CC=C6) C5=C4) =NC=N3) =C2C.Cl.Cl
Molecular Formula
C27H29FN8O3Cl2
Molecular Weight
603.48
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
MBS3610133-01BMS-599626 2HCl
M20147-01BMS 599626 2HCl
BUP04728-01BMS 599626 2HCl (873837-23-1 (HCl) )
MBS5751809BMS 599626 2HCl (873837-23-1 (HCl))
T2610L-01BMS-599626 2HCL (714971-09-2 Free base)
MBS130816-01BMS-599626
262829-01BMS 599626
A2822-5AC480 (BMS-599626)
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A3252-5.1BMS-599626 Hydrochloride

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