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ML216

CAT: 0013-GTR19168456-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168456-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML216 (CID-49852229) is a potent and selective inhibitor of the BLM helicase with an IC50 of 1.8 μM, demonstrating over 28-fold selectivity against RECQ1, RECQ5, and E. coli UvrD. This tool compound is used in vitro to study DNA repair mechanisms, replication stress, and genomic instability associated with Bloom syndrome.
CAS Number
1430213-30-1
Product Name Alternative
Inhibit, ML216, ML-216, ML 216, Inhibitor, helicase, DNA, DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, chromatid, CID 49852229, CID49852229, CID-49852229, BLM helicase, BLM, anti-proliferative, Anticancer, sister, WRN, RNASynthesis, RNA Synthesis, toxicity, unwinding
Field of Research
Cell Biology, Molecular Biology
Purity
96.83% (May vary between batches)
Solubility
DMSO:5 mg/mL (13.04 mM)
Smiles
Fc1ccc (NC (=O) Nc2nnc (s2) -c2ccncc2) cc1C (F) (F) F
Molecular Formula
C15H9F4N5OS
Molecular Weight
383.32
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
B8015-5.1ML216
A21754-10ML216 10mg
A21754-5ML216 5mg
A21754-100ML216 100mg
A21754-50ML216 50mg
A21754-25ML216 25mg
MBS130630-01ML216(CID-49852229)
SF1172-25mgML216 (BLM helicase inhibitor)
A21754-10mM-DML216 10mM * 1mL in DMSO
217222BLM Helicase Inhibitor, ML216 (ML-216, 1- (4-Fluoro-3- (trifluoromethyl) phenyl) -3- (5- (pyridin-4-yl) -1,3,4-thiadiazol-2-yl) urea)

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