(S) - (+) -Rolipram

CAT: 0013-GTR19168208-01Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19168208-01Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

(+) -Rolipram is a selective PDE4 inhibitor with an IC50 of 0.75 μM against the human monocyte enzyme. This compound exhibits anti-inflammatory and CNS antidepressant activities in research models, though it is less potent than its (R) -enantiomer. It is widely used in vitro and in vivo to study PDE4 biology and inflammation-related pathways.

CAS Number

85416-73-5

Product Name Alternative

(S) -Rolipram, (S) (+) Rolipram, (S) (+) Rolipram, (+) -Rolipram, Apoptosis, cAMP, necrosis, PDE4, inhibit, mononuclear, Inhibitor, factor, Phosphodiesterase (PDE), phosphodiesterase, TNFα, Rolipram, S- Rolipram, S- (+) -Rolipram, tumor

Field of Research

Cell Biology, Metabolism Research

Purity

99.14% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (99.88 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.26 mM)

Smiles

COc1ccc (cc1OC1CCCC1) [C@H]1CNC (=O) C1

Molecular Formula

C16H21NO3

Molecular Weight

275.34

Storage Conditions

-20°C

Notes

For research use only.

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A4328-50	Rolipram
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(S) - (+) -Rolipram

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