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Tasquinimod

CAT: 0013-GTR19168167-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168167-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tasquinimod (ABR-215050) is an orally active small molecule with antiangiogenic and antitumor properties. It functions as an S100A9 inhibitor and binds the HDAC4 Zn2+ domain with high affinity (Kd 10-30 nM) . This agent has been investigated in preclinical in vivo models for cancers like prostate carcinoma and in vitro for immunomodulatory effects.
CAS Number
254964-60-8
Product Name Alternative
ABR215050, ABR-215050, ABR 215050, inhibit, HDAC4, HDAC, Inhibitor, Histone deacetylases, Tasquinimod
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.30% (May vary between batches)
Solubility
2% DMSO+40% PEG300+5% Tween-80+53% Saline:1 mg/mL (2.46 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:9 mg/mL (22.15 mM) ; DMSO:65 mg/mL (159.96 mM)
Smiles
COc1cccc2n (C) c (=O) c (C (=O) N (C) c3ccc (cc3) C (F) (F) F) c (O) c12
Molecular Formula
C20H17F3N2O4
Molecular Weight
406.36
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
A3860-5Tasquinimod

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