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VUF 10166

CAT: 0013-GTR19168137-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19168137-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VUF10166 is a highly potent and selective competitive antagonist of the 5-HT3A receptor, exhibiting sub-nanomolar affinity (Ki = 0.04 nM) with significantly reduced activity at heteromeric 5-HT3AB receptors. This selectivity makes it a valuable research tool for in vitro and in vivo studies investigating the specific roles of 5-HT3A receptors in neurotransmission, emesis, and anxiety-related behaviors.
CAS Number
155584-74-0
Product Name Alternative
5-hydroxytryptamine Receptor, 5-HT3 receptor ligand, 5-HT3A, 5-HT3AB, 5HTReceptor, agonist, 5HT Receptor, 5-HT Receptor, inhibit, neurotransmission, Inhibitor, Serotonin Receptor, VUF10166, VUF-10166, VUF 10166
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.52% (May vary between batches)
Solubility
DMSO:26.3 mg/mL (100.1 mM) ; Ethanol:26.3 mg/mL (100.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.61 mM)
Smiles
CN1CCN (CC1) c1nc2ccccc2nc1Cl
Molecular Formula
C13H15ClN4
Molecular Weight
262.74
Storage Conditions
-20°C
Notes
For research use only.

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