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G007-LK

CAT: 0013-GTR19168029-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19168029-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
G007-LK is a potent and selective dual inhibitor of tankyrase 1 (TNKS1) and tankyrase 2 (TNKS2), exhibiting IC50 values of 46 nM and 25 nM, respectively. This small molecule is a valuable chemical probe for studying Wnt/β-catenin signaling in cancer research and has been utilized in both cellular and in vivo models to investigate tankyrase function.
CAS Number
1380672-07-0
Product Name Alternative
Inhibitor, G007 LK, G007LK, G-007-LK, G007-LK, inhibit, PARP, bcatenin, beta-catenin, betacatenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, poly ADP ribose polymerase, TNKS1, TNKS2, βcatenin
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.63% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (6.23 mM) ; DMSO:93 mg/mL (175.48 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CS (=O) (=O) c1ccc (nc1) -c1nnc (\C=C\c2nnc (o2) -c2ccc (cc2) C#N) n1-c1ccccc1Cl
Molecular Formula
C25H16ClN7O3S
Molecular Weight
529.96
Storage Conditions
-20°C
Notes
For research use only.

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