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PD168393

CAT: 0013-GTR19167943-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167943-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PD168393 is a potent and irreversible EGFR inhibitor (IC50: 0.70 nM) that selectively targets Cys-773. It demonstrates high selectivity, showing no activity against PKC, FGFR, PDGFR, or insulin receptor. This compound is widely used in vitro and in vivo to study EGFR-driven oncogenic signaling and tumor growth.
CAS Number
194423-15-9
Product Name Alternative
IGF1R, Inhibitor, Insulin Receptor, HER1, Epidermal growth factor receptor, epidermoid carcinoma, ErbB-1, EGFR, FGFR, inhibit, PDGFR, PD168393, PD-168393, PD 168393, Autophagy, Apoptosis, PKC, tumor
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
99.04% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:40 mg/mL (108.34 mM)
Smiles
Brc1cccc (Nc2ncnc3ccc (NC (=O) C=C) cc23) c1
Molecular Formula
C17H13BrN4O
Molecular Weight
369.22
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
A2024-5PD168393
A12725-10PD168393 10mg
A12725-2PD168393 2mg
A12725-1PD168393 1mg
A12725-100PD168393 100mg
A12725-25PD168393 25mg
A12725-5PD168393 5mg
A12725-50PD168393 50mg
SF5418-5mgPD168393 (EGFR inhibitor)

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