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Sarcosine

CAT: 0013-GTR19167904-02Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19167904-02Size:1 g
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Description
Sarcosine is a dual-function small molecule that competitively inhibits the glycine transporter GlyT1 and acts as a co-agonist at NMDA receptors. It is widely used in neuroscience research to study glutamatergic neurotransmission, synaptic plasticity, and related mechanisms in models of psychiatric and neurological disorders.
CAS Number
107-97-1
Product Name Alternative
Cognitive, depression, dysfunction, Endogenous Metabolite, Methylaminoacetic acid, Methylglycine, N-methyl-D-aspartate, N-methylglycine, N-Methylaminoacetic acid, inhibit, Inhibitor, Glycine transporters, GlyT, GlyT1, EndogenousMetabolite, Sarcosin, Sarcosine, Sarcosinic acid, schizophrenia
Field of Research
Metabolism Research, Neuroscience
Purity
99.34% (May vary between batches)
Solubility
DMSO:Insoluble; H2O:250 mg/mL (2806.15 mM)
Smiles
CNCC (O) =O
Molecular Formula
C3H7NO2
Molecular Weight
89.09
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Sarcosine

Sarcosine is a N-alkylglycine that is the N-methyl derivative of glycine. It is an intermediate in the metabolic pathway of glycine. It has a role as a glycine transporter 1 inhibitor, a glycine receptor agonist, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a N-methyl-amino acid, a member of N-methylglycines and a N-alkylglycine. It is a conjugate base of a sarcosinium. It is a conjugate acid of a sarcosinate. It is a tautomer of a sarcosine zwitterion.

CAS Number107-97-1
PubChem CID1088
IUPAC Name2-(methylamino)acetic acid
Molecular FormulaC3H7NO2
Molecular Weight89.09
XLogP-2.8
Topological Polar Surface Area49.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Heavy Atom Count6
Formal Charge0
Complexity52
SMILES
CNCC(=O)O
InChI
InChI=1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)
InChIKey
FSYKKLYZXJSNPZ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Sarcosine
CAS: 107-97-1
CID: 1088
Formula: C3H7NO2
MW: 89.09
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight89.09
XLogP3-2.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count2
Exact Mass89.047678466
Monoisotopic Mass89.047678466
Topological Polar Surface Area49.3 Ų
Heavy Atom Count6
Formal Charge0
Complexity52.8
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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CatalogName
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