Products for Research Use Only

2-HBA

CAT: 0013-GTR19167666-03Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19167666-03Size:1 ml x 10 mM (in DMSO)
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Description
2-HBA is a synthetic curcumin analog that activates the Keap1-Nrf2-ARE signaling pathway, leading to the upregulation of detoxifying enzymes. This inducer is a valuable research tool for studying oxidative stress response and cytoprotection in both cellular and animal models.
CAS Number
131359-24-5
Product Name Alternative
Inhibit, Inhibitor, NQO1, 2 HBA, 2HBA, 2-HBA, Caspase
Field of Research
Cell Biology, Metabolism Research, Protein Biochemistry
Purity
95.01% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.02 mM) ; DMSO:100 mg/mL (375.53 mM)
Smiles
Oc1ccccc1\C=C\C (=O) \C=C\c1ccccc1O
Molecular Formula
C17H14O3
Molecular Weight
266.29
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(1E,4E)-1,5-bis(2-hydroxyphenyl)penta-1,4-dien-3-one
CAS Number131359-24-5
PubChem CID5472867
IUPAC Name(1E,4E)-1,5-bis(2-hydroxyphenyl)penta-1,4-dien-3-one
Molecular FormulaC17H14O3
Molecular Weight266.29
XLogP3.4
Topological Polar Surface Area57.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count20
Formal Charge0
Complexity338
SMILES
C1=CC=C(C(=C1)/C=C/C(=O)/C=C/C2=CC=CC=C2O)O
InChI
InChI=1S/C17H14O3/c18-15(11-9-13-5-1-3-7-16(13)19)12-10-14-6-2-4-8-17(14)20/h1-12,19-20H/b11-9+,12-10+
InChIKey
YNVAHBUBGBLIEY-WGDLNXRISA-N
Chemical Structure
2D Structure
2D structure of (1E,4E)-1,5-bis(2-hydroxyphenyl)penta-1,4-dien-3-one
CAS: 131359-24-5
CID: 5472867
Formula: C17H14O3
MW: 266.29
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight266.29
XLogP33.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass266.094294304
Monoisotopic Mass266.094294304
Topological Polar Surface Area57.5 Ų
Heavy Atom Count20
Formal Charge0
Complexity338
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes