Products for Research Use Only

AMG-47a

CAT: 0013-GTR19167539-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167539-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG-47a is a potent small molecule inhibitor of lymphocyte-specific protein tyrosine kinase (Lck), suppressing T-cell proliferation. It also acts as a selective degrader of the KRASG12V oncoprotein, as demonstrated in cellular studies, making it a valuable tool for oncology and immunology research.
CAS Number
882663-88-9
Product Name Alternative
Janus kinase, JAK, immune, kinases, Inhibitor, inhibit, family, Lck, AMG 47a, AMG47a, AMG-47a, cell, cytoplamic, p38 MAPK, p38MAPK, receptor, signal, specific, Src, responses, VEGFR, Vascular endothelial growth factor receptor, transduction, tyrosine
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:34 mg/mL (63.48 mM)
Smiles
Cc1ccc (cc1-c1ccc2nc (NCCN3CCOCC3) ncc2c1) C (=O) Nc1cccc (c1) C (F) (F) F
Molecular Formula
C29H28F3N5O2
Molecular Weight
535.56
Storage Conditions
-20°C
Notes
For research use only.