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(E/Z) -Necrosulfonamide

CAT: 0013-GTR19167532-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167532-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Necrosulfonamide is a selective inhibitor of the MLKL protein, a key executor of necroptosis. This cell-permeable compound is a valuable tool for investigating necroptotic pathways in both cellular and animal models of inflammatory and degenerative diseases.
CAS Number
432531-71-0
Product Name Alternative
Necrosis (MLKL), Necrosulfonamide
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction
Purity
97.62% (May vary between batches)
Solubility
DMSO:25 mg/mL (54.17 mM)
Smiles
COc1nccnc1NS (=O) (=O) c1ccc (NC (=O) C=Cc2ccc (s2) [N+] ([O-]) =O) cc1
Molecular Formula
C18H15N5O6S2
Molecular Weight
461.47
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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HY-100573A-01(E/Z) -Necrosulfonamide
217559MLKL Inhibitor, Necrosulfonamide ((E) -N- (4- (N- (3-Methoxypyrazin-2-yl) sulfamoyl) phenyl) -3- (5-nitrothiophene-2-yl) acrylamide, Mixed Lineage Kinase Domain-like Protein Inhibitor, Necrosome Inhibitor II, Necrosulfonamide) discontinued
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