Products for Research Use Only
RegisterLogin

PF-06454589

CAT: 0013-GTR19167447-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19167447-02Size:1 ml x 10 mM (in DMSO)
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PF-06454589 is a highly effective small molecule LRRK2 kinase inhibitor. It is a valuable research tool for studying Parkinson's disease mechanisms in both cellular (in vitro) and animal (in vivo) models, aiding in the investigation of LRRK2's role in neurobiology.
CAS Number
1527473-30-8
Product Name Alternative
PF 06454589, PF06454589, PF-06454589, Inhibitor, Leucine-rich repeat kinase 2, G2019S LRRK2, inhibit, LRRK2, parkinson's disease
Field of Research
Cell Biology
Purity
96.29% (May vary between batches)
Solubility
DMSO:9 mg/mL (31.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.52 mM)
Smiles
Cn1cc (cn1) -c1c[nH]c2ncnc (N3CCOCC3) c12
Molecular Formula
C14H16N6O
Molecular Weight
284.32
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

PF-06454589
CAS Number1527473-30-8
PubChem CID72706837
IUPAC Name4-[5-(1-methylpyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine
Molecular FormulaC14H16N6O
Molecular Weight284.32
XLogP0.7
Topological Polar Surface Area71.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count21
Formal Charge0
Complexity363
SMILES
CN1C=C(C=N1)C2=CNC3=C2C(=NC=N3)N4CCOCC4
InChI
InChI=1S/C14H16N6O/c1-19-8-10(6-18-19)11-7-15-13-12(11)14(17-9-16-13)20-2-4-21-5-3-20/h6-9H,2-5H2,1H3,(H,15,16,17)
InChIKey
VNWKCLDQBNSJJO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of PF-06454589
CAS: 1527473-30-8
CID: 72706837
Formula: C14H16N6O
MW: 284.32
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight284.32
XLogP30.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass284.13855916
Monoisotopic Mass284.13855916
Topological Polar Surface Area71.9 Ų
Heavy Atom Count21
Formal Charge0
Complexity363
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19224314-01PF-06745013
GTR19222974-01PF-06764427
GTR19218956-01PF-07208254
GTR19218556-01PF-07059013
GTR19213053-01PF-17
GTR19212475-01PF-06455943
GTR19211449-01PF-446687
GTR19210318-01PF-4211
GTR19209610-01PF-06658607
GTR19209586-01PF-303

Alternative Products

CatalogName
532463PF-06454589
A22595-50PF-06454589 50mg
A22595-200PF-06454589 200mg
A22595-10PF-06454589 10mg
A22595-25PF-06454589 25mg
A22595-5PF-06454589 5mg
A22595-500PF-06454589 500mg
A22595-100PF-06454589 100mg
A22595-2PF-06454589 2mg
A22595-10mM-DPF-06454589 10mM * 1mL in DMSO

Popular Products