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Aprocitentan

CAT: 0013-GTR19167372-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167372-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aprocitentan (ACT-132577) is a dual endothelin receptor antagonist, selectively blocking both ETA and ETB subtypes. It is a research compound used in preclinical studies to investigate the endothelin system's role in cardiovascular diseases, including resistant hypertension, as evidenced in both in vitro and in vivo models.
CAS Number
1103522-45-7
Product Name Alternative
Inhibit, EndothelinReceptor, Endothelin Receptor, ET-B, ET-A, Inhibitor, Aprocitentan, ACT 132577, ACT132577, ACT-132577
Field of Research
Pharmacology & Drug Discovery
Purity
96.60% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.66 mM) ; DMSO:65 mg/mL (119.01 mM)
Smiles
NS (=O) (=O) Nc1ncnc (OCCOc2ncc (Br) cn2) c1-c1ccc (Br) cc1
Molecular Formula
C16H14Br2N6O4S
Molecular Weight
546.19
Storage Conditions
-20°C
Notes
For research use only.

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