Products for Research Use Only
RegisterLogin

VU6015929

CAT: 0013-GTR19167329-02Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19167329-02Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
VU6015929 is a potent and selective small molecule inhibitor of DDR1 and DDR2, with IC50 values of 4.67 nM and 7.39 nM, respectively. This compound is a valuable research tool for investigating the roles of these receptors in fibrosis and cancer progression in both cellular and animal models.
CAS Number
2442597-56-8
Product Name Alternative
Discoidin Domain Receptor, Discoidin Domain Receptor (DDR), DiscoidinDomainReceptor, DiscoidinDomainReceptor (DDR), DDR, DDR2, DDR1, VU 6015929, VU6015929, VU-6015929
Field of Research
Signal Transduction
Purity
97.07% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.3 mM) ; DMSO:250 mg/mL (515.01 mM)
Smiles
Cn1ccc (n1) -c1cncc (CNc2cc (ccc2F) C (=O) Nc2cccc (OC (F) (F) F) c2) c1
Molecular Formula
C24H19F4N5O2
Molecular Weight
485.43
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-Fluoro-3-(((5-(1-methyl-1H-pyrazol-3-yl)pyridin-3-yl)methyl)amino)-N-(3-(trifluoromethoxy)phenyl)benzamide
CAS Number2442597-56-8
PubChem CID145925694
IUPAC Name4-fluoro-3-[[5-(1-methylpyrazol-3-yl)-3-pyridinyl]methylamino]-N-[3-(trifluoromethoxy)phenyl]benzamide
Molecular FormulaC24H19F4N5O2
Molecular Weight485.4
XLogP4.4
Topological Polar Surface Area81.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Heavy Atom Count35
Formal Charge0
Complexity699
SMILES
CN1C=CC(=N1)C2=CN=CC(=C2)CNC3=C(C=CC(=C3)C(=O)NC4=CC(=CC=C4)OC(F)(F)F)F
InChI
InChI=1S/C24H19F4N5O2/c1-33-8-7-21(32-33)17-9-15(12-29-14-17)13-30-22-10-16(5-6-20(22)25)23(34)31-18-3-2-4-19(11-18)35-24(26,27)28/h2-12,14,30H,13H2,1H3,(H,31,34)
InChIKey
IZKVIUJIUTXIRH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-Fluoro-3-(((5-(1-methyl-1H-pyrazol-3-yl)pyridin-3-yl)methyl)amino)-N-(3-(trifluoromethoxy)phenyl)benzamide
CAS: 2442597-56-8
CID: 145925694
Formula: C24H19F4N5O2
MW: 485.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight485.4
XLogP34.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count7
Exact Mass485.14748751
Monoisotopic Mass485.14748751
Topological Polar Surface Area81.1 Ų
Heavy Atom Count35
Formal Charge0
Complexity699
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA8898-5.1VU6015929

Popular Products